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Voici les éléments 61-70 de 79
Chroniques génomiques - La longévité des sébastes
(EDP Sciences, 2022)
The existence of a number of highly similar rockfish species with very different life spans has motivated extensive DNA sequencing studies that have uncovered strong selection for genes involved in DNA maintenance and in ...
Chroniques génomiques - Réparation de l’ADN et longévité : les rongeurs et nous
(EDP Sciences, 2022)
Large differences in maximum longevity exist between different rodent species. Determination of the spontaneous and mutagen-induced mutation rates in these species by single (somatic) cell sequencing suggests more efficient ...
CRISPR : le Nobel, enfin…
(EDP Sciences, 2021)
Après Marie Curie, en 1903 et 1911, Irène Joliot-Curie en 1935, Françoise Barré-Sinoussi en 2008, Esther Duflo (franco-américaine) en 2019, Emmanuelle Charpentier est la cinquième française à décrocher un Prix Nobel (le ...
Chroniques génomiques - Mutations somatiques et longévité
(EDP Sciences, 2022)
New approaches allow precise measurement of somatic mutations in tissues. Applied to a diverse set of mammals, these methods show that somatic mutation load increases with age (as expected) but reaches similar levels near ...
Vers une thérapie génique pour la progéria ?
(EDP Sciences, 2021)
Hutchinson-Gilford Progeria (acute premature aging) is caused by a de novo point mutation in the lamin A gene. Recently, this mutation has been accurately corrected by base editing in patient cell lines and in a mouse ...
Chroniques génomiques - La « dé-extinction » du mammouth laineux, un « Colossal » canular ?
(EDP Sciences, 2022)
Reports of a mammoth cloning project on-going under George Church’s supervision appear periodically in the press. Close examination of the available evidence indicates that there is indeed such a project (carried out in a ...
Chroniques génomiques - Chiens, loups et gènes
(EDP Sciences, 2022)
The most significant polymorphism associated with dog size occurs in the region of the
IGF1
gene and concerns a single base change in a neighbouring lncRNA. The “small” (C) ...
Chroniques génomiques - Un cadeau empoisonné
(EDP Sciences, 2020)
GWAS analysis of severe Covid patients implicates a major locus on chromosome 3. The corresponding 50 kb segment appears to originate from Neanderthal/Sapiens crossings, raising interesting evolutionary questions.
ADN et portait-robot : où en est-on ?
(EDP Sciences, 2020)
The prediction of a person’s aspect from analysis of an anonymous DNA sample has made significant progress in the last decade. Pigmentation (eyes, hair and, more recently, skin colour) can now be determined with good ...
Chroniques génomiques - Les traces génétiques de la traite des esclaves
(EDP Sciences, 2020)
More than 10 million enslaved Africans were transported to the Americas between 1500 and 1900. Recent genetic studies investigate regional African ancestry components in present-day Africa-Americans, and allow comparison ...