The existence of a number of highly similar rockfish species with very different life spans has motivated extensive DNA sequencing studies that have uncovered strong selection for genes involved in DNA maintenance and in ...

Large differences in maximum longevity exist between different rodent species. Determination of the spontaneous and mutagen-induced mutation rates in these species by single (somatic) cell sequencing suggests more efficient ...

Après Marie Curie, en 1903 et 1911, Irène Joliot-Curie en 1935, Françoise Barré-Sinoussi en 2008, Esther Duflo (franco-américaine) en 2019, Emmanuelle Charpentier est la cinquième française à décrocher un Prix Nobel (le ...

New approaches allow precise measurement of somatic mutations in tissues. Applied to a diverse set of mammals, these methods show that somatic mutation load increases with age (as expected) but reaches similar levels near ...

Hutchinson-Gilford Progeria (acute premature aging) is caused by a de novo point mutation in the lamin A gene. Recently, this mutation has been accurately corrected by base editing in patient cell lines and in a mouse ...

Reports of a mammoth cloning project on-going under George Church’s supervision appear periodically in the press. Close examination of the available evidence indicates that there is indeed such a project (carried out in a ...

The most significant polymorphism associated with dog size occurs in the region of the IGF1 gene and concerns a single base change in a neighbouring lncRNA. The “small” (C) ...

GWAS analysis of severe Covid patients implicates a major locus on chromosome 3. The corresponding 50 kb segment appears to originate from Neanderthal/Sapiens crossings, raising interesting evolutionary questions.

The prediction of a person’s aspect from analysis of an anonymous DNA sample has made significant progress in the last decade. Pigmentation (eyes, hair and, more recently, skin colour) can now be determined with good ...

More than 10 million enslaved Africans were transported to the Americas between 1500 and 1900. Recent genetic studies investigate regional African ancestry components in present-day Africa-Americans, and allow comparison ...