Après Marie Curie, en 1903 et 1911, Irène Joliot-Curie en 1935, Françoise Barré-Sinoussi en 2008, Esther Duflo (franco-américaine) en 2019, Emmanuelle Charpentier est la cinquième française à décrocher un Prix Nobel (le ...

A systematic study analysing the exomes of several thousand individuals indicates that each of them carries at least one strongly deleterious mutation that is innocuous in a heterozygote but results in a severe phenotype ...

Transgenerational effects have long been expected in children from parents exposed to radiation from atomic bombs in Japan in 1945 or from the Chernobyl disaster in 1986. These effects have in fact proven hard to detect. ...

The elimination of some senescent cells by « senolytic » compounds can greatly improve the health of aged mice and in some cases reverse the effects of aging. Using a microbial exposure system that closely models coronavirus ...

In vivo gene editing has been achieved in a phase I clinical trial and results in a strong reduction of the level of a pathogenic protein. While preliminary, these results open the way for many ...

Face shape is genetically determined, but the underlying genetic architecture is complex, and precise definition of facial structures is essential for any serious study. Recent work, based on objective definition of facial ...

New approaches allow precise measurement of somatic mutations in tissues. Applied to a diverse set of mammals, these methods show that somatic mutation load increases with age (as expected) but reaches similar levels near ...

An ingenious system for generating thousands of point mutations in yeast genes and measuring their effect on fitness shows convincingly that, for the chosen subset of representative non-essential genes, silent mutations ...

It is commonly believed that a dog’s breed predicts its behaviour. A 2019 paper seemed to confirm this, but had some serious limitations. An extensive new study shows that, in fact, breed is not a good predictor of behaviour ...