Recherche
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Analysis of the association between CDH2 gene polymorphism and osteoarthritis risk
(EDP Sciences, 2018)
Objective: to define the cadherin 2 (CDH2) gene polymorphism in Chinese osteoarthritis and control populations and to explore the correlation between CDH2 gene polymorphism and the risk of osteoarthritis. Method: a total ...
Computational QSAR model combined molecular descriptors and fingerprints to predict HDAC1 inhibitors
(EDP Sciences, 2018)
The dynamic balance between acetylation and deacetylation of histones plays a crucial role in the epigenetic regulation of gene expression. It is equilibrated by two families of enzymes: histone acetyltransferases and ...