Recherche
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Chroniques génomiques - Les débuts de CRISPR en thérapie génique
(Éditions EDK, Groupe EDP Sciences, 2016)
Two clinical trials using CRISPR technology to engineer the T cells of cancer patients by inactivating the gene for immune checkpoint molecule PD-1 are (almost) underway, one in the USA and the other in China. The less ...
Chroniques génomiques - Le Graal de Grail est-il un mirage ?
(Éditions EDK, Groupe EDP Sciences, 2016)
A newly established company called Grail and spun out from Illumina promises to develop a “liquid biopsy” test suitable for asymptomatic cancer detection and general screening. While the necessary sensitivity may be ...
Chroniques génomiques - 23andMe et le mal des transports
(Éditions EDK, Groupe EDP Sciences, 2016)
A Genome Wide Association Study on propensity to motion sickness published by 23andMe gives interesting results, shows validity for self-reported phenotypic information and underlines the value of the model developed by ...
Chroniques génomiques - Les spermatozoïdes de l’obésité
(Éditions EDK, Groupe EDP Sciences, 2016)
A demonstration of (somewhat) specific differential RNA content and DNA methylation in sperm from obese individuals opens the possibility of epigenetic transmission to offspring.