Recherche
Voici les éléments 1-10 de 24
Chroniques génomiques : Une publication impulsive…
(Éditions EDK/Groupe EDP Sciences, 2011)
Chroniques génomiques - Thérapie génique germinale, le retour ?
(Éditions EDK, Groupe EDP Sciences, 2015)
The recent development of a powerful and flexible genome editing technique (the CRISP-cas9 method) accelerates tremendously the production of animal models and will significantly enhance the perspectives of (somatic) gene ...
Chroniques génomiques - Sommet de Washington : feu orange pour la thérapie germinale ?
(Éditions EDK, Groupe EDP Sciences, 2016)
The summit organised in early December 2015 considered in depth the various issues (technical, scientific, societal and ethical) raised by the prospect of genome editing using the extremely effective CRISPR system. Germline ...
Chroniques génomiques - CRISPR-Cas9, une nouvelle donne pour la thérapie génique
(Éditions EDK, Groupe EDP Sciences, 2015)
Targeted modification of genes (“gene editing”) is made much easier by the recently developed CRISPR-Cas9 system. This has raised alarm about possible uses of this technology for germline modification of the human genome; ...
Chroniques génomiques - Les spermatozoïdes de l’obésité
(Éditions EDK, Groupe EDP Sciences, 2016)
A demonstration of (somewhat) specific differential RNA content and DNA methylation in sperm from obese individuals opens the possibility of epigenetic transmission to offspring.
Chroniques génomiques : Snip et histoire familiale : le match !
(Éditions EDK/Groupe EDP Sciences, 2013)
Chroniques génomiques : Épigénétique et résilience
(Éditions EDK/Groupe EDP Sciences, 2013)
The likelihood of adult psychiatric problems is increased by childhood trauma, particularly so in carriers of certain alleles of certain genes. I discuss here a recent paper that sheds light on the mechanism of this effect, ...
Chroniques génomiques - Couleur de la peau chez l’homme : de nouvelles surprises
(EDP Sciences, 2019)
Careful GWAS analysis of a group of mixed-ancestry Latino-American individuals
reveals the role of a new “light” variant of the MSFD12 gene
which appears to originate in some of the ...
Chroniques génomiques - Modification ciblée du génome : une nouvelle approche prometteuse
(Éditions EDK, Groupe EDP Sciences, 2017)
A new approach, based on the use of peptide nucleic acid molecules to form triple helices and promote locus-specific recombination, demonstrates potential for in vivo gene correction at clinically significant levels and ...
Chroniques génomiques - Les pièges de l’amélioration
(EDP Sciences, 2019)
Inactivation of the CCR5 gene by CRISPR editing in human
embryos, as recently attempted in China, was touted as a positive change for the
babies involved since it was expected to ...