Chroniques génomiques - Couleur de la peau chez l’homme : de nouvelles surprises

Abstract

Careful GWAS analysis of a group of mixed-ancestry Latino-American individuals reveals the role of a new “light” variant of the MSFD12 gene which appears to originate in some of the Asian populations that migrated into the Americas 15,000 years ago. This indicates convergent evolution of sparsely pigmented skin at high latitudes, and highlights the interest of performing GWAS studies in non-European populations.