Recherche
Voici les éléments 21-30 de 46
Chroniques génomiques - Du bon usage d’un test non invasif
(Éditions EDK, Groupe EDP Sciences, 2015)
Chroniques génomiques - Cancer : les trois époques de la médecine personnalisée :
(Éditions EDK, Groupe EDP Sciences, 2017)
Since the completion of the first human DNA sequence, genomic approaches have penetrated into cancer research and therapy: first through expression profiling for diagnostic, prognostic and predictive purposes, then by ...
Chroniques Génomiques - Les chimères du dépistage
(Éditions EDK, Groupe EDP Sciences, 2017)
The use of circulating tumour DNA to screen for cancer in asymptomatic individuals is the goal of Grail, initially set up by Illumina. This company is now raising a large amount of capital to develop this project on a much ...
Chroniques génomiques - Les limites de l’« oncologie de précision »
(EDP Sciences, 2019)
The concept of precision oncology is straightforward, but the actual results of treating advanced cancer patients with the targeted drug suggested by genomic analysis have been generally disappointing, indicating that this ...
Recherche cibles, désespérément : Chroniques génomiques
(Éditions EDK, Groupe EDP Sciences, 2015)
In clinical oncology, obtaining sequence data from tumour samples has become practical in terms of logistics, turnover time and costs. The major issue now is the interpretation of this sequence to define actionable targets, ...
Bases alternatives et organismes synthétiques : Chroniques Génomiques
(EDP Sciences, 2018)
Alternative bases that can fit into the DNA double helix have now been used in vivo to direct the synthesis of proteins incorporating unnatural amino acids. This bioengineering feat is significant at both the conceptual ...
Chroniques génomiques - Dépister les cancers asymptomatiques ?
(EDP Sciences, 2018)
A recent publication describes a sophisticated “liquid biopsy” procedure that analyses both tumoral DNA and proteins present in peripheral blood to provide sensitive detection of different types of cancer. These results ...
Hémophilie : la thérapie génique, enfin… : Chroniques Génomiques
(EDP Sciences, 2018)
Recent efforts at gene therapy for haemophilia A and B using AAV-derived vectors show durable expression of coagulation factors at significant levels, resulting in almost complete correction of the phenotype. This is the ...
Cancer : Thérapies « complémentaires » et observance du traitement anti-tumoral font-elles bon ménage ?
(EDP Sciences, 2018)
A recent paper shows that cancer patients using complementary therapies in addition to conventional treatment have distinctly worse outcomes. Analysis of the data shows that they are much more likely to refuse one component ...
Chroniques génomiques - Une approche pragmatique pour gérer les traitements onéreux
(Éditions EDK, Groupe EDP Sciences, 2017)
Inflated drug prices necessarily raise the issue of rational allocation of health care resources. The system operated by the NICE agency in the UK attempts to do this by calculating the cost per quality-adjusted life year ...