Recherche
Voici les éléments 141-146 de 146
Chroniques génomiques - Séquençage d’ADN, la fin d’un quasi-monopole ?
(EDP Sciences, 2023)
DNA sequencing costs have steadily decreased during the last decade, but the dominant technology (short-read sequencing, Illumina) has seen comparatively little competition after an initial flurry. This phase is now over, ...
Chroniques génomiques - Les traces génétiques de la peste noire
(EDP Sciences, 2023)
Genetic analysis of human populations before and after the great plague pandemic in the late Middle Ages reveals immune-related loci at which specific alleles have been selected because they conferred (partial) resistance ...
Chroniques génomiques - Naissance d’un gène
(EDP Sciences, 2023)
The availability of an extensive set of vertebrate genome sequences, together with large-scale transcriptome studies, has allowed the discovery of numerous non-canonical ORFs (usually quite short) with evidence of ...
Chroniques génomiques - Le dépistage du cancer sauve-t-il vraiment des vies ?
(EDP Sciences, 2023)
Systematic screening for specific cancers has been shown to reduce cancer-specific mortality, but has not demonstrated an effect on all-cause mortality. This paradox is due to minor but frequent risks of screening bearing ...
Chroniques génomiques - Les secrets des variants
(EDP Sciences, 2023)
Most sequence variants encountered in medical genetics are of unknown significance, and their interpretation is a major stumbling block. Building on the successful AlphaFold system, the DeepMind group at Google has built ...
Chroniques génomiques - Taille à l’âge adulte : une myriade de locus
(EDP Sciences, 2023)
The combination of 281 GWAS studies for adult height leads to the identification of 12,111 SNP in 7,209 loci that together account for essentially all SNP heritability for this trait: there is no longer any significant ...