Chroniques génomiques - Ces bons mutants qui éliminent les tumeurs

Jordan, Bertrand

doi:10.1051/medsci/2021239

dc.contributor.author	Jordan, Bertrand	-
dc.date.accessioned	2023-02-10T16:30:08Z
dc.date.available	2023-02-10T16:30:08Z
dc.date.issued	2022
dc.identifier.citation	Jordan, Bertrand ; Ces bons mutants qui éliminent les tumeurs : Chroniques génomiques, Med Sci (Paris), Vol. 38, N° 1 ; p. 101-106 ; DOI : 10.1051/medsci/2021239
dc.identifier.issn	1958-5381
dc.identifier.uri	http://hdl.handle.net/10608/12490
dc.description.abstract	Most (>90%) of the nascent tumours present in murine oesophageal epithelium after mutagen treatment disappear during the following months. This elimination is driven by mutant (but phenotypically normal) clones that gradually outcompete and eliminate the neoplastic clones. This novel mechanism, demonstrated in the mouse, is probably active in humans as well and may have important clinical implications.	en
dc.language.iso	fr
dc.publisher	EDP Sciences
dc.relation.ispartof	Forum
dc.rights	Article en libre accès - License CC BY 4.0	fr
dc.rights	Médecine/Sciences - Inserm - SRMS	fr
dc.rights.uri	http://creativecommons.org/licenses/by/4.0
dc.source	M/S. Médecine sciences [ISSN papier : 0767-0974 ; ISSN numérique : 1958-5381], Vol. 38, N° 1; p. 101-106
dc.subject.mesh	Animaux	fr
dc.subject.mesh	Transformation cellulaire néoplasique	fr
dc.subject.mesh	Cellules cultivées	fr
dc.subject.mesh	Clones cellulaires	fr
dc.subject.mesh	Souris	fr
dc.subject.mesh	Tumeurs	fr
dc.title	Chroniques génomiques - Ces bons mutants qui éliminent les tumeurs	fr
dc.title.alternative	Good mutant clones eliminate nascent tumours	en
dc.type	Article
dc.contributor.affiliation	ADÉS (Anthropologie bioculturelle, droit, éthique et santé) UMR CNRS 7268, Aix Marseille université, Établissement français du sang. CoReBio PACA, case 901, Parc scientifique de Luminy , 13288 Marseille Cedex 09 , France
dc.identifier.doi	10.1051/medsci/2021239
dc.identifier.pmid	35060896