dc.contributor.author | Jordan, Bertrand | - |
dc.date.accessioned | 2018-05-30T11:38:36Z | |
dc.date.available | 2018-05-30T11:38:36Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Jordan, Bertrand ; CRISPR-Cas9, une nouvelle donne pour la thérapie génique, Med Sci (Paris), 2015, Vol. 31, N° 11 ; p. 1035-1038 ; DOI : 10.1051/medsci/20153111018 | |
dc.identifier.issn | 1958-5381 | |
dc.identifier.uri | http://hdl.handle.net/10608/8723 | |
dc.description.abstract | Targeted modification of genes (“gene editing”) is made much easier by the recently developed CRISPR-Cas9 system. This has raised alarm about possible uses of this technology for germline modification of the human genome; however this technology has less controversial applications, notably for somatic gene therapy with already some striking demonstrations in animal systems. Because of its precision and relative ease of use, CRISPR can be expected to drive a revolution in gene therapy and to turn it into a more mainstream approach. | en |
dc.language.iso | fr | |
dc.publisher | Éditions EDK, Groupe EDP Sciences | |
dc.relation.ispartof | Forum | |
dc.rights | Article en libre accès | fr |
dc.rights | Médecine/Sciences - Inserm - SRMS | fr |
dc.source | M/S. Médecine sciences [ISSN papier : 0767-0974 ; ISSN numérique : 1958-5381], 2015, Vol. 31, N° 11; p. 1035-1038 | |
dc.subject.mesh | Animaux | fr |
dc.subject.mesh | Recherche biomédicale | fr |
dc.subject.mesh | Systèmes CRISPR-Cas | fr |
dc.subject.mesh | Clustered regularly interspaced short palindromic repeats | fr |
dc.subject.mesh | Dependovirus | fr |
dc.subject.mesh | Industrie pharmaceutique | fr |
dc.subject.mesh | Génie génétique | fr |
dc.subject.mesh | Thérapie génétique | fr |
dc.subject.mesh | Humains | fr |
dc.subject.mesh | ARN guide | fr |
dc.subject.mesh | législation et jurisprudence | fr |
dc.subject.mesh | tendances | fr |
dc.subject.mesh | physiologie | fr |
dc.subject.mesh | génétique | fr |
dc.subject.mesh | méthodes | fr |
dc.title | Chroniques génomiques - CRISPR-Cas9, une nouvelle donne pour la thérapie génique | fr |
dc.title.alternative | CRISPR-Cas9, a new chance for somatic gene therapy | en |
dc.type | Article | |
dc.contributor.affiliation | UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d’adultes la Timone, 264, rue Saint-Pierre, 13385 Marseille Cedex 05, France | |
dc.contributor.affiliation | CoReBio PACA, case 901, parc scientifique de Luminy, 13288 Marseille Cedex 09, France | |
dc.identifier.doi | 10.1051/medsci/20153111018 | |
dc.identifier.pmid | 26576611 | |