Parcourir médecine/sciences 2014 par auteur "Jordan, Bertrand"
Voici les éléments 1-9 de 9
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Chroniques génomiques - De l’exome à l’avatar : vers une « oncologie de précision » ?
Jordan, Bertrand (Éditions EDK, Groupe EDP Sciences, 2014)According to recent reports, the success rate of targeted therapy directed by “actionable mutations” found in tumour DNA is rather low (10 to 20%). Interesting attempts have been made to improve this by establishing mouse ... -
Chroniques génomiques - Hétérogénéité des tumeurs : l’apport du séquençage sur cellules individuelles
Jordan, Bertrand (Éditions EDK, Groupe EDP Sciences, 2014)The heterogeneity of tumours is now beginning to be documented precisely by single-cell new-generation sequencing. Recently published results on breast tumours show that each of the cells analysed displays a unique pattern ... -
Chroniques génomiques - Les leçons inattendues d’Hiroshima
Jordan, Bertrand (Éditions EDK, Groupe EDP Sciences, 2014)One of the initial motivations for the Genome project was to improve the detection of possible mutations in children of atomic bomb survivors. In fact it has proved very difficult to find any genetic effect in these ... -
Chroniques génomiques - Les « gènes » de la schizophrénie
Jordan, Bertrand (Éditions EDK, Groupe EDP Sciences, 2014)Very large-scale GWAS analyses confirm the genetic complexity of schizophrenia and provide some new leads to understand the etiology of the condition. -
Chroniques génomiques - L’invasion des tests non invasifs
Jordan, Bertrand (EDP Sciences, 2014)Non-invasive prenatal testing is becoming commonplace, but, in addition, other tests using only a blood sample are being developed and will have a significant impact, notably in oncology. -
Chroniques génomiques - Variants rares et explosion démographique
Jordan, Bertrand (Éditions EDK, Groupe EDP Sciences, 2014)The abundance of rare variants in human DNA is the consequence of tremendous recent expansion of our population. Careful measurement of neutral variants in a European population points to more recent and more rapid expansion ... -
Course à la lune en biologie : Chroniques génomiques
Jordan, Bertrand (Éditions EDK, Groupe EDP Sciences, 2014)Three recent and very large projects aim to integrate several “omics” approaches in order to promote pro-active medicine and to create a “Wellness industry”. -
Grandes manœuvres autour des profils génétiques en libre accès
Jordan, Bertrand (EDP Sciences, 2014) -
Les retombées cliniques du séquençage de nouvelle génération : Chroniques génomiques
Jordan, Bertrand (Éditions EDK, Groupe EDP Sciences, 2014)New-generation sequencing is already in routine clinical use, notably for the search of actionable mutations in oncology, and for non-invasive prenatal diagnostics. More applications are developing and will soon enter ...