Recherche
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Chroniques génomiques - Cancer : les trois époques de la médecine personnalisée :
(Éditions EDK, Groupe EDP Sciences, 2017)
Since the completion of the first human DNA sequence, genomic approaches have penetrated into cancer research and therapy: first through expression profiling for diagnostic, prognostic and predictive purposes, then by ...
Hémophilie : la thérapie génique, enfin… : Chroniques Génomiques
(EDP Sciences, 2018)
Recent efforts at gene therapy for haemophilia A and B using AAV-derived vectors show durable expression of coagulation factors at significant levels, resulting in almost complete correction of the phenotype. This is the ...
Chroniques génomiques : Le Junk DNA n’est plus ce qu’il était
(EDP Sciences, 2020)
A systematic search for non-conventional open reading frames in human DNA reveals a large number of small ORFs encoding peptides generally smaller than 100 amino-acids. These ORFs are transcribed and translated into small ...
Chroniques génomiques - Clap de fin pour le « gène de l’homosexualité »
(EDP Sciences, 2020)
Evidence for a “homosexuality gene” was claimed in the early 1990’s on the basis of linkage studies that, by current criteria, were woefully underpowered. Indeed, follow up studies gave contradictory results. Genome-wide ...