Recherche
Voici les éléments 1-10 de 18
Chroniques génomiques - De l’exome à l’avatar : vers une « oncologie de précision » ?
(Éditions EDK, Groupe EDP Sciences, 2014)
According to recent reports, the success rate of targeted therapy directed by “actionable mutations” found in tumour DNA is rather low (10 to 20%). Interesting attempts have been made to improve this by establishing mouse ...
Chroniques génomiques - CRISPR-Cas9, une nouvelle donne pour la thérapie génique
(Éditions EDK, Groupe EDP Sciences, 2015)
Targeted modification of genes (“gene editing”) is made much easier by the recently developed CRISPR-Cas9 system. This has raised alarm about possible uses of this technology for germline modification of the human genome; ...
Chroniques génomiques : L’insoutenable complexité des cancers
(Éditions EDK/Groupe EDP Sciences, 2011)
Chroniques génomiques : Remise en cause du « dogme central »
(Éditions EDK/Groupe EDP Sciences, 2011)
Chroniques génomiques - Les Argonautes ont-ils perdu le Nord ?
(Éditions EDK, Groupe EDP Sciences, 2017)
A novel gene editing procedure based on a nuclease from the Argonaute protein family was described in mid-2016 and appeared to provide significant advantages over the now widely used CRISPR-Cas9 system. Attempts by numerous ...
Chroniques génomiques : Du bon usage des exomes
(EDK, 2010)
Hémophilie : la thérapie génique, enfin… : Chroniques Génomiques
(EDP Sciences, 2018)
Recent efforts at gene therapy for haemophilia A and B using AAV-derived vectors show durable expression of coagulation factors at significant levels, resulting in almost complete correction of the phenotype. This is the ...
Chroniques génomiques : Des signatures sans valeur ?
(Éditions EDK/Groupe EDP Sciences, 2012)
Chroniques génomiques : Néandertal et Homo sapiens : To meet, or not to meet?
(Éditions EDK/Groupe EDP Sciences, 2012)
Chroniques génomiques - La longévité des sébastes
(EDP Sciences, 2022)
The existence of a number of highly similar rockfish species with very different life spans has motivated extensive DNA sequencing studies that have uncovered strong selection for genes involved in DNA maintenance and in ...