Recherche
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Chroniques génomiques - Biopsies liquides, une révolution en cancérologie ?
(Éditions EDK, Groupe EDP Sciences, 2015)
The detection and analysis of circulating tumour DNA and/or circulating tumour cells in the blood of cancer patients open new possibilities for cancer characterisation and management. The approach has generated much ...
Chroniques génomiques - Cancer : les trois époques de la médecine personnalisée :
(Éditions EDK, Groupe EDP Sciences, 2017)
Since the completion of the first human DNA sequence, genomic approaches have penetrated into cancer research and therapy: first through expression profiling for diagnostic, prognostic and predictive purposes, then by ...
Chroniques génomiques - Les limites de l’« oncologie de précision »
(EDP Sciences, 2019)
The concept of precision oncology is straightforward, but the actual results of treating advanced cancer patients with the targeted drug suggested by genomic analysis have been generally disappointing, indicating that this ...
Recherche cibles, désespérément : Chroniques génomiques
(Éditions EDK, Groupe EDP Sciences, 2015)
In clinical oncology, obtaining sequence data from tumour samples has become practical in terms of logistics, turnover time and costs. The major issue now is the interpretation of this sequence to define actionable targets, ...
Chroniques génomiques - Scores polygéniques et risque de cancer
(EDP Sciences, 2020)
Risk assessment for a cancer type with moderate heritability can be accurately performed using a relatively small number of SNPs detected by GWAS analyses to calculate a polygenic risk score (PRS) that has definite clinical ...