Recherche
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Chroniques génomiques - Balayage du génome et repérage des personnes à risque : Des GWAS aux GPS
(EDP Sciences, 2018)
The accumulation of extensive repositories linking phenotypic and genetic information, together with new computation methods, makes it possible to derive polygenic scores for susceptibility to common diseases that turn out ...
Chroniques génomiques - Scores polygéniques et risque de cancer
(EDP Sciences, 2020)
Risk assessment for a cancer type with moderate heritability can be accurately performed using a relatively small number of SNPs detected by GWAS analyses to calculate a polygenic risk score (PRS) that has definite clinical ...
Chroniques génomiques - Scores polygéniques : vers l’embryon à la carte ?
(EDP Sciences, 2020)
A new company is offering extensive genetic analysis of embryos during an in vitro fertilisation procedure, allowing the derivation of polygenic scores for several diseases and embryo choice based on these results. Polygenic ...