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Chroniques génomiques - Extension du domaine du codage : l’ADN hachimoji
(EDP Sciences, 2019)
The synthesis of four new nucleotide analogues that can form hydrogen bonds within the DNA double helix and can be incorporated without distortion of the structure extends the possibilities of synthetic biology. Although ...
Chroniques génomiques - Synthétique, vous avez dit « Synthétique » ?
(Éditions EDK, Groupe EDP Sciences, 2016)
The synthesis of a minimal bacterial genome comprising only 473 genes is an impressive achievement, yet it is only a step towards a really synthetic genome based on first principles: this set of genes was derived from a ...
Bases alternatives et organismes synthétiques : Chroniques Génomiques
(EDP Sciences, 2018)
Alternative bases that can fit into the DNA double helix have now been used in vivo to direct the synthesis of proteins incorporating unnatural amino acids. This bioengineering feat is significant at both the conceptual ...