Growth hormone (GH) is the major hormone secreted by the pituitary gland and its pattern of secretion is sexually differentiated in many species. It is a pleiotropic hormone which acts as a growth factor in bone and muscle ...

Cyclic nucleotide phosphodiesterases (PDE) are classified into five families (PDE I to V) according to their primary sequence, their substrate specificities and their sensitivities to different modulators. PDE I, PDE II ...