Mécanismes d’action et toxicités potentielles des
                    anticorps monoclonaux

Bejan-Angoulvant, Theodora; Alexandre, Joachim

doi:10.1051/medsci/2019208

dc.contributor.author	Bejan-Angoulvant, Theodora	-
dc.contributor.author	Alexandre, Joachim	-
dc.date.accessioned	2020-12-07T10:30:02Z
dc.date.available	2020-12-07T10:30:02Z
dc.date.issued	2019
dc.identifier.citation	Bejan-Angoulvant, Theodora ; Alexandre, Joachim ; Mécanismes d’action et toxicités potentielles des anticorps monoclonaux, Med Sci (Paris), Vol. 35, N° 12 ; p. 1114-1120 ; DOI : 10.1051/medsci/2019208
dc.identifier.issn	1958-5381
dc.identifier.uri	http://hdl.handle.net/10608/10526
dc.description.abstract	Monoclonal antibodies are therapeutic monoclonal Ig that act by highly specific binding to their target antigen and by interacting with the immune system. Their side effects are mainly related to their mechanism of action. The most frequent adverse effects are infusion reactions. Post-marketing surveillance is essential for identifying adverse reactions and improving knowledge of their mechanism of action.	en
dc.language.iso	fr
dc.publisher	EDP Sciences
dc.relation.ispartof	Anticorps monoclonaux : de la complexité du passage du laboratoire à l’homme
dc.rights	Article en libre accès - License CC BY 4.0 [http://creativecommons.org/licenses/by/4.0]	fr
dc.rights	Médecine/Sciences - Inserm - SRMS	fr
dc.source	M/S. Médecine sciences [ISSN papier : 0767-0974 ; ISSN numérique : 1958-5381], Vol. 35, N° 12; p. 1114-1120
dc.subject.mesh	Animaux	fr
dc.subject.mesh	Anticorps monoclonaux	fr
dc.subject.mesh	Effets secondaires indésirables des médicaments	fr
dc.subject.mesh	Humains	fr
dc.subject.mesh	Système immunitaire	fr
dc.subject.mesh	Surveillance post-commercialisation des produits de santé	fr
dc.subject.mesh	Transduction du signal	fr
dc.subject.mesh	effets indésirables	fr
dc.subject.mesh	immunologie	fr
dc.subject.mesh	usage thérapeutique	fr
dc.subject.mesh	épidémiologie	fr
dc.subject.mesh	étiologie	fr
dc.subject.mesh	effets des médicaments et substances chimiques	fr
dc.subject.mesh	métabolisme	fr
dc.title	Mécanismes d’action et toxicités potentielles des anticorps monoclonaux	fr
dc.title.alternative	Mechanism of action and adverse effects of monoclonal antibodies	en
dc.type	Article
dc.contributor.affiliation	Service de Pharmacologie médicale, CHRU de Tours ; EA 7501, GICC, équipe PATCH, Université de Tours, 37000 Tours, France
dc.contributor.affiliation	LabEx MabImprove,
dc.contributor.affiliation	Service de Pharmacologie, CHU Caen ; EA4650, Normandie Université, Caen, 14000, France
dc.identifier.doi	10.1051/medsci/2019208
dc.identifier.pmid	31903925