dc.contributor.author | Jordan, Bertrand | - |
dc.date.accessioned | 2020-12-07T10:17:28Z | |
dc.date.available | 2020-12-07T10:17:28Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Jordan, Bertrand ; Bébés CRISPR : Anatomie d’une transgression, Med Sci (Paris), Vol. 35, N° 3 ; p. 266-270 ; DOI : 10.1051/medsci/2019034 | |
dc.identifier.issn | 1958-5381 | |
dc.identifier.uri | http://hdl.handle.net/10608/10368 | |
dc.description.abstract | Analysing the data recently presented by Jiankui He and assuming that it is authentic shows that the goal of abolishing the expression of CCR5 may have been reached for one of the resulting twins, although this remains to be proven. However, the canonical delta32 mutation has not been achieved. The various preliminary experiments and controls give some confidence that major off-target modifications have not occurred; again, this is difficult to exclude. Clearly, the requirements of perfect technical mastery of the process have not been met, to say nothing of the requirements for complete transparency and full societal approval. | en |
dc.language.iso | fr | |
dc.publisher | EDP Sciences | |
dc.relation.ispartof | Repères | |
dc.rights | Article en libre accès - License CC BY 4.0 [http://creativecommons.org/licenses/by/4.0] | fr |
dc.rights | Médecine/Sciences - Inserm - SRMS | fr |
dc.source | M/S. Médecine sciences [ISSN papier : 0767-0974 ; ISSN numérique : 1958-5381], Vol. 35, N° 3; p. 266-270 | |
dc.subject.mesh | Bioéthique | fr |
dc.subject.mesh | Systèmes CRISPR-Cas | fr |
dc.subject.mesh | Chine | fr |
dc.subject.mesh | Clonage d'organisme | fr |
dc.subject.mesh | Congrès comme sujet | fr |
dc.subject.mesh | Résistance à la maladie | fr |
dc.subject.mesh | Recherche sur l'embryon | fr |
dc.subject.mesh | Délétion de gène | fr |
dc.subject.mesh | Édition de gène | fr |
dc.subject.mesh | VIH (Virus de l'Immunodéficience Humaine) | fr |
dc.subject.mesh | Infections à VIH | fr |
dc.subject.mesh | Humains | fr |
dc.subject.mesh | Nouveau-né | fr |
dc.subject.mesh | Inventions | fr |
dc.subject.mesh | Mutation | fr |
dc.subject.mesh | Récepteurs CCR5 | fr |
dc.subject.mesh | Inconduite scientifique | fr |
dc.subject.mesh | tendances | fr |
dc.subject.mesh | génétique | fr |
dc.subject.mesh | éthique | fr |
dc.subject.mesh | méthodes | fr |
dc.title | Bébés CRISPR : Anatomie d’une transgression | fr |
dc.title.alternative | CRISPR babies: technology and transgression | en |
dc.type | Article | |
dc.contributor.affiliation | UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS ; CoReBio PACA,
case 901, Parc scientifique de Luminy, 13288
Marseille Cedex 09,
France | |
dc.identifier.doi | 10.1051/medsci/2019034 | |
dc.identifier.pmid | 30931913 | |