Rechercher le terme 'Génomique'
Définition : 1/ Analyse du fonctionnement d’un organisme, d’un organe ou d’un cancer donné, en tenant compte de son génome 2/ Étude à l’échelle du génome du fonctionnement de l’organisme, d’un organe, d’une pathologie, etc.
Documents relatifs à ce terme :
Voici les éléments 201-220 de 211
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Chroniques génomiques - Taille à l’âge adulte : une myriade de locus
(EDP Sciences, 2023)The combination of 281 GWAS studies for adult height leads to the identification of 12,111 SNP in 7,209 loci that together account for essentially all SNP heritability for this trait: there is no longer any significant ... -
23andMe , ou la chute d’une licorne *
(EDP Sciences, 2025)23andMe, a company pioneering on-demand genetic profiling, has attracted much attention, millions of customers and very significant investments, as well as some lucrative collaborations with the pharmaceutical industry. ... -
La « médecine mitochondriale » à l’aune du quatrième plan national maladies rares (PNMR4) : L’exemple du projet MITOMICS
(EDP Sciences, 2025)Le projet MITOMICS vise à développer une base de données cliniques et « multi-omiques » provenant de patients atteints de maladies mitochondriales, à l’échelle nationale, afin de mieux comprendre les mécanismes moléculaires ... -
Les thérapies géniques peuvent-elles devenir abordables ?
(EDP Sciences, 2025)Twenty gene therapies have now been approved in the USA by the FDA, but their stratospheric price tag (often above one million USD per patient) makes them essentially unaffordable for most. A systematic study of the various ... -
L’ADN comme mémoire informatique (suite)
(EDP Sciences, 2025)Using DNA as a storage medium for digital data promises ultra-high density and safe long-term storage. A number of companies are actively working in this space; they have demonstrated the feasibility of the approach and ... -
Maladie de Huntington : enfin un mécanisme !
(EDP Sciences, 2025)A beautiful piece of work using extensive single-cell studies illuminates the mechanism of Huntington’s disease: the somatic expansion of the (CAG)n tract, very slow at first but accelerating once a critical repeat length ... -
Épidémiologie moléculaire par séquençage des acides nucléiques d’origine virale présents dans les eaux usées
(EDP Sciences, 2025)L’analyse métagénomique des acides nucléiques présents dans les eaux usées est un outil épidémiologique prometteur pour suivre la propagation des virus dans de grands bassins démographiques. Son utilisation lors de la ... -
Séquençage de l’ADN : La fin d’un quasi-monopole
(EDP Sciences, 2025)For the last decade, the field of DNA sequencing has been dominated by a single company, Illumina, with very limited competition. However, a new method with superior performance and lower cost has recently been announced ... -
Séquençage par nanopores : les protéines aussi ?
(EDP Sciences, 2025)DNA sequencing using nanopores is now well established. Could the approach be extended to proteins ? There are a number of difficulties but work by many groups has shown proof-of-principle solutions for most of them. Further ... -
GRAIL , un rêve de médecine préventive ?
(EDP Sciences, 2024)Multi-Cancer Early Detection is a highly popular topic, bringing the hope of being able to detect very early, non-symptomatic cancers and allowing more successful therapy. A major company in this space is GRAIL, which has ... -
L’édition de nouvelle génération
(EDP Sciences, 2024)Recent work on bacterial insertion sequences reveals that some of them use an RNA sequence (called Bridge RNA or Seek RNA) to define both donor and target DNA specificity. This opens the way to easy insertion of kilobase ...