The accumulation of extensive repositories linking phenotypic and genetic information, together with new computation methods, makes it possible to derive polygenic scores for susceptibility to common diseases that turn out ...

Careful GWAS analysis of a group of mixed-ancestry Latino-American individuals reveals the role of a new “light” variant of the MSFD12 gene which appears to originate in some of the ...

Inactivation of the CCR5 gene by CRISPR editing in human embryos, as recently attempted in China, was touted as a positive change for the babies involved since it was expected to ...

Risk assessment for a cancer type with moderate heritability can be accurately performed using a relatively small number of SNPs detected by GWAS analyses to calculate a polygenic risk score (PRS) that has definite clinical ...

The combination of 281 GWAS studies for adult height leads to the identification of 12,111 SNP in 7,209 loci that together account for essentially all SNP heritability for this trait: there is no longer any significant ...

GWAS analyses for skin colour performed on a series of diverse African groups reveal new loci involved in this phenotype and, surprisingly, the presence within several African populations of the “light” allele of the SLC24A5 ...

Comme on l’a dit et répété dans ces colonnes [1–3], la valeur prédictive des profils génétiques à base de Snip vendus par 23andMe, Navigenics et autres « entreprises DTC » (direct to consumer) est très faible pour ne pas ...