Parcourir par sujet "Exome"
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Chroniques génomiques - De l’exome à l’avatar : vers une « oncologie de précision » ?
(Éditions EDK, Groupe EDP Sciences, 2014)According to recent reports, the success rate of targeted therapy directed by “actionable mutations” found in tumour DNA is rather low (10 to 20%). Interesting attempts have been made to improve this by establishing mouse ... -
Chroniques génomiques - Nos défauts génétiques cachés
(EDP Sciences, 2021)A systematic study analysing the exomes of several thousand individuals indicates that each of them carries at least one strongly deleterious mutation that is innocuous in a heterozygote but results in a severe phenotype ... -
L’ADN fœtal révélé
(EDP Sciences, 2024)New developments in the analysis of maternal cell-free DNA now allow complete analysis of the foetal exome. This makes possible an important extension of the breadth of prenatal diagnostics but raises significant ethical ...