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Voici les éléments 11-20 de 25
Chroniques génomiques - Les Argonautes ont-ils perdu le Nord ?
(Éditions EDK, Groupe EDP Sciences, 2017)
A novel gene editing procedure based on a nuclease from the Argonaute protein family was described in mid-2016 and appeared to provide significant advantages over the now widely used CRISPR-Cas9 system. Attempts by numerous ...
Chroniques génomiques - CRISPR sur embryons humains : une nouvelle étape
(Éditions EDK, Groupe EDP Sciences, 2017)
Viable human embryos carrying a disease mutation have now been corrected by CRISPR-Cas9 editing. Although the correction is not perfect, and the embryos have not been implanted, this brings us closer to human germline ...
Chroniques génomiques - Le monde caché des clones mutants dans les tissus normaux
(EDP Sciences, 2019)
Careful sequencing studies on small samples of normal oesophageal epithelium reveal the presence of very abundant cellular clones harbouring mutations in known cancer genes (and elsewhere). The number and size of these ...
Chroniques génomiques - La sénescence en passe d’être vaincue ?
(EDP Sciences, 2018)
Senescent cells are involved in many age-related diseases, and the effects of their elimination by “senolytic” drugs is an active research field. A recent paper describes a convenient murine model of induced senescence and ...
Chroniques génomiques : The sound of silence
(Éditions EDK/Groupe EDP Sciences, 2012)
Chroniques génomiques : Rare is frequent
(Éditions EDK/Groupe EDP Sciences, 2012)
Chroniques génomiques - L’ADN comme mémoire informatique ?
(EDP Sciences, 2018)
The very high information density of DNA has prompted speculations on its use for information storage. The high costs of DNA synthesis and sequencing made this highly unpractical; however recent progress (notably array ...
Chroniques génomiques - De HGP-write aux « super-cellules »
(EDP Sciences, 2018)
The HGP-write project, announced in 2016 but not really implemented yet, comes back as a project aimed at constructing an “ultra-safe” human cell line fully resistant to virus infection and with other desirable characteristics. ...
Chroniques génomiques : Néandertal et Homo sapiens : To meet, or not to meet?
(Éditions EDK/Groupe EDP Sciences, 2012)
Chroniques génomiques : Perseverare diabolicum ?
(Éditions EDK/Groupe EDP Sciences, 2012)