Recherche
Voici les éléments 91-100 de 167
Chroniques Génomiques - Les chimères du dépistage
(Éditions EDK, Groupe EDP Sciences, 2017)
The use of circulating tumour DNA to screen for cancer in asymptomatic individuals is the goal of Grail, initially set up by Illumina. This company is now raising a large amount of capital to develop this project on a much ...
Un malentendu
(Éditions EDK, Groupe EDP Sciences, 2017)
Chroniques génomiques - Les limites de l’« oncologie de précision »
(EDP Sciences, 2019)
The concept of precision oncology is straightforward, but the actual results of treating advanced cancer patients with the targeted drug suggested by genomic analysis have been generally disappointing, indicating that this ...
CCR5 et longévité : une rétraction
(EDP Sciences, 2019)
Chroniques génomiques - Cent ans après, le retour de la phagothérapie ?
(EDP Sciences, 2019)
Bacteriophages were advocated as therapeutic agents more than a century ago, but the advent of antibiotics relegated them to a very minor role. Today, multi-drug resistant bacteria are a serious health problem, and phage ...
Relativisme, ambiguïtés et vérités scientifiques non alternatives
(Éditions EDK, Groupe EDP Sciences, 2017)
Recherche cibles, désespérément : Chroniques génomiques
(Éditions EDK, Groupe EDP Sciences, 2015)
In clinical oncology, obtaining sequence data from tumour samples has become practical in terms of logistics, turnover time and costs. The major issue now is the interpretation of this sequence to define actionable targets, ...
Chroniques génomiques - 23andMe ou comment (très bien) valoriser ses clients
(Éditions EDK, Groupe EDP Sciences, 2015)
The announcement of several deals between the DTC genetics firm 23andMe and Genentech, Pfizer and other corporations reveals the real business model of the company: selling access to sets of characterized patients for ...
Chroniques génomiques - Variants fréquents et rares, caractères multigéniques et héritabilité perdue
(Éditions EDK, Groupe EDP Sciences, 2017)
Recently, a systematic (but limited) search for rare variants implicated in adult height, a highly polygenic trait, has uncovered a number of new variants for which the effect size is inversely correlated with the minor ...
Bases alternatives et organismes synthétiques : Chroniques Génomiques
(EDP Sciences, 2018)
Alternative bases that can fit into the DNA double helix have now been used in vivo to direct the synthesis of proteins incorporating unnatural amino acids. This bioengineering feat is significant at both the conceptual ...